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This data is NERC-funded but not held by the EIDC. This data is archived in the European Molecular Biology Laboratory- European Bioinformatics Institute (EMBL-EBI) MetaboLights (https://www.ebi.ac.uk/metabolights), accession number MTBLS3749. Multi ‘omics’ data were collected from lines of Daphnia magna resurrected from Lake Ring (Denmark). The genome, methylome, transcriptome, accessible chromatin (ATAC), and metabolome was characterized from these lines, spanning >100 years.