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Health

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  • We do not fully understand how important types (species) of bacteria and packages of genetic material (genes) coding for antibiotic resistance move between humans, animals and the environment, or where, how and why antibiotic resistance emerges. This study looked in detail on a genetic level at bacteria in farm animals, human/animal sewage, sewage treatment works and rivers, to work out the complex network of transmission of important antibiotic-resistant bacteria and antibiotic resistance genes. The overarching aim was to use this information to work out how best to slow down the spread of antibiotic resistance between humans, livestock and the environment. Sampling occurred at three discrete time-points : January-April 2017, June-July 2017, October-November 2017. Research was funded through NERC grant NE/N019989/1. The environmental REsistome: confluence of Human and Animal Biota in antibiotic resistance spread (REHAB)

  • We do not fully understand how important types (species) of bacteria and packages of genetic material (genes) coding for antibiotic resistance move between humans, animals and the environment, or where, how and why antibiotic resistance emerges. This study looked in detail on a genetic level at bacteria in farm animals, human/animal sewage, sewage treatment works and rivers, to work out the complex network of transmission of important antibiotic-resistant bacteria and antibiotic resistance genes. The overarching aim was to use this information to work out how best to slow down the spread of antibiotic resistance between humans, livestock and the environment. Sampling occurred at three discrete time-points : January-April 2017, June-July 2017, October-November 2017. Research was funded through NERC grant NE/N019989/1. The environmental REsistome: confluence of Human and Animal Biota in antibiotic resistance spread (REHAB)

  • This data is NERC-funded but not held by the EIDC. This data is archived in the National Center for Biotechnology Information (NCBI). Data consists of metagenomic datasets of faecal pellets collected from six-week old C57Bl/6 female mice orally infected with Citrobacter rodentium harbouring genetically modified antimicrobial resistance plasmids pC15-1a or RP4, respectively. Infections performed in May 2018. Faecal pellets collected prior to infection, and six days post-infection, and used to study changes in the methylation profile of organisms present in the intestine.

  • This data is NERC-funded but not held by the EIDC. This data is archived in the European Nucleotide Archive (ENA). This dataset contains sequences of the genomic DNA of gut microbiota of calves in response to preventive antibiotic therapy florfenicol obtained by DNA-seq. Importantly, the dataset also contains sequences of genes resistant to different antibiotics. The dataset was created from faecal samples (n=3) of the antibiotic treated animals over seven days and samples (n=3) of animals which have not been subjected to the antibiotic over the same time.

  • This data is NERC-funded but not held by the EIDC. This data is archived in the European Nucleotide Archive (ENA). This dataset contains sequences of 16S rRNA genes of gut microbiota of calves in response to preventive antibiotic therapy florfenicol by DNA-seq. The dataset was created from faecal samples (n=3) of the antibiotic treated animals over seven days and samples (n=3) of animals which have not been subjected to the antibiotic over the same time.

  • This data is NERC-funded but not held by the EIDC. This data is archived in the UK Data Service ReShare repository. The dataset contains data from a randomised controlled trial study which aimed to provide an evaluation of a smartphone app-based wellbeing intervention. The data comprise participant demographics and questionnaire responses supplied at the pre-, post- and follow-up phases of the study and geolocation data returned by the app as the participants entered areas designated as urban green spaces.

  • The dataset provides observational information on events when humans are in contact with poultry in rural and urban Bangladesh. Data were collected during observation periods of three hours duration in three settings where humans and poultry have close interactions: rural households with domestic poultry and small-scale commercial farms in rural areas of Tangail district and market stalls that sell, slaughter and process live poultry in Dhaka city. Observations on hygiene or handwashing behaviours that take place before or after contact with poultry, poultry products (eggs, meat) or poultry waste (bedding, faeces or carcasses) were also recorded. A structured observation sheet was used to record the number of occurrences of pre-defined activities. The objective was to record the types of contact behaviours and proportion of human-poultry interactions that could result in human exposure to antibiotic-resistant bacteria carried by poultry. The research was part of a wider research project, Spatial and Temporal Dynamics of Antimicrobial Resistance (AMR) Transmission from the Outdoor Environment to Humans in Urban and Rural Bangladesh. The research was funded by NERC/BBSRC/MRC on behalf of the Antimicrobial Resistance Cross-Council Initiative, award NE/N019555/1. Full details about this dataset can be found at https://doi.org/10.5285/76f52a38-7a2c-49a3-b86f-cc40205459ef

  • These dataset files show the calibration of a sensor for mercury (II) ions using a Fluorimeter and either HgCl2 or HgNO3. A range of different sample conditions are tested, including sensor concentrations and relative proportions of water and a methanol co-solvent (required for solubility of the probe). Also tested was the ability of acid to affect the probes sensitivity to mercury as nitric acid is needed for the stability of HgNO3 as an analyte. File names listed show the concentration of sensor and the ratio of water to methanol tested. Inductively coupled plasma mass spectrometry (ICP-MS) data are also given these are used to validate the sensors calibration and also to monitor the levels of soluble mercury content of dental amalgam samples held at either (11⁰C or 37⁰C) in water and saliva. The supernatant of these suspensions is filtered and measured using ICP-MS to give the data as reported. Full details about this nonGeographicDataset can be found at https://doi.org/10.5285/bc82f15b-8db6-4398-bfec-655a1eecf2d7

  • 'This data is NERC-funded but not held by the EIDC. This data is archived in the European Nucleotide Archive (ENA). Data consist of antisense RNA produced by calf gut microbiota in response to antibiotic treatment.

  • Prevalence of quinolone qnrS resistance gene in the aquatic environment from the Avon river catchment area receiving treated wastewater from 5 wastewater treatment plants (WWTPs), serving 1.5 million people and accounting for 75% of inhabitants living in the catchment area in the South West of England. Funded by NERC Grant NE/N019261/1 Full details about this dataset can be found at https://doi.org/10.5285/102f8141-2a9a-4ffd-89f6-961af36ddcb3