Molluscan Shell Matrix Proteins

The database contains fasta sequences from UniProt and associated metadata for molluscan shell matrix proteins (SMPs). The database only contains SMPs that have been experimentally validated to be present in molluscan shell matrices (based on the publication(s) attached to the UniProtID). Metadata includes information on functional domains present in the sequence, as detected by InterproScan. With the advent of Next Generation Sequencing technologies, it is computationally resource intensive to run sequence similarity algorithms on all published data. Moreover, it is impractical to sort through hundreds of sequence similarity search results when working with non-model organisms, since pre-established functional annotations of sequences are generally not available. Therefore, this database was created in order to provide a targeted molluscan biomineralization dataset for sequence similarity algorithms (such as BLAST). Database created as part of doctoral research, funded under Marie Curie Innovative Training Networks (ITN) - Calcium in the Changing Environment (CACHE - Grant agreement 605051).